ChemInform Abstract: The 17-Spiro Lactide of Cortienic Acid: A Probe for Studying the Active Sites of Steroidal Receptors.
Abstract
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ChemInform Abstract
The spiro lactide ring of title steroid (I) adopts half-chair conformation, with the two ester carbonyl groups aligned and directly opposing each other. The crystal packing diagram shows that the molecules are connected in a two-dimensional zigzag pattern by hydrogen bonds involving the 11-hydroxy and 3-keto groups.