Volume 31, Issue 7
Natural Products
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ChemInform Abstract: The 17-Spiro Lactide of Cortienic Acid: A Probe for Studying the Active Sites of Steroidal Receptors.

Asiloe J. Mora

Asiloe J. Mora

Lab. Cristalogr., Fac. Cienc., Dep. Quim., Univ. Los Andres, Merida 5251, Venez.

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Belkis M. Ramirez

Belkis M. Ramirez

Lab. Cristalogr., Fac. Cienc., Dep. Quim., Univ. Los Andres, Merida 5251, Venez.

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Gerzon Delgado

Gerzon Delgado

Lab. Cristalogr., Fac. Cienc., Dep. Quim., Univ. Los Andres, Merida 5251, Venez.

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Roy Little

Roy Little

Lab. Cristalogr., Fac. Cienc., Dep. Quim., Univ. Los Andres, Merida 5251, Venez.

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First published: 10 June 2010

Abstract

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ChemInform Abstract

The spiro lactide ring of title steroid (I) adopts half-chair conformation, with the two ester carbonyl groups aligned and directly opposing each other. The crystal packing diagram shows that the molecules are connected in a two-dimensional zigzag pattern by hydrogen bonds involving the 11-hydroxy and 3-keto groups.

chemical structure image

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