Isocyclic Compounds
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ChemInform Abstract: An Efficient, Palladium-Catalyzed Amination of Aryl Bromides.
First published: 14 June 2010
Abstract
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ChemInform Abstract
In the presence of catalytic Pd(O-Ac)2 and the chelating ligand Xantphos, aryl bromides (I) are efficiently coupled with primary and secondary amines to yield the anilines (III) selectively. The procedure allows amination of both electron-poor and electron-rich aryl bromides.
