ChemInform Abstract: A General Approach for the Enantioselective Synthesis of anti-β-Hydroxy-α-amino Acids: Preparation of an Oxazolidine-Functionalized Chiral Glycine Equivalent.
Abstract
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ChemInform Abstract
An efficient and highly stereoselective synthesis of the new chiral glycine equivalent (V), an advanced intermediate for the preparation of anti-β-hydroxy-α-amino acids, from (R)-(-)-phenylglycinol is reported. Its structure and configuration is corroborated by X-ray analysis.