Volume 29, Issue 31
Preparative Organic Chemistry
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ChemInform Abstract: Efficient Transformation of Nitrile into Amide under Mild Condition.

M. K. BASU

M. K. BASU

Inst. Chem., Acad. Sin., Nankang, Taipei 11529, Taiwan

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F.-T. LUO

F.-T. LUO

Inst. Chem., Acad. Sin., Nankang, Taipei 11529, Taiwan

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First published: 20 June 2010

Abstract

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ChemInform Abstract

Addition of controlled amounts of trimethylsilyl chloride and water to a variety of nitriles (I) results in high yielding conversion to amides (II) under mild conditions.

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