ChemInform Abstract: Efficient Syntheses of (E)-5-(2-Bromovinyl)-2′-deoxy-4′-thiouridine; a Nucleoside Analogue with Potent Biological Activity.
Abstract
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ChemInform Abstract
Two efficient, alternative routes to the synthesis of the title thiouridine [cf. protected precursors (VII) and (X)], one of the most potent and selective antiherpesvirus compounds known, are developed.