Volume 29, Issue 11
Heterocyclic Compounds
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ChemInform Abstract: Heterocyclization of Acetylketene N,S-Acetals with Benzoylcyanamide.

V. A. DOROKHOV

V. A. DOROKHOV

Inst. org. khim. im. Zelinskogo Ross. Akad. nauk, Moskva 117913, Russia

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A. V. KOMKOV

A. V. KOMKOV

Inst. org. khim. im. Zelinskogo Ross. Akad. nauk, Moskva 117913, Russia

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V. S. BOGDANOV

V. S. BOGDANOV

Inst. org. khim. im. Zelinskogo Ross. Akad. nauk, Moskva 117913, Russia

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First published: 23 June 2010

Abstract

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ChemInform Abstract

Reaction of the acetylketene N,S-acetals (I) with benzoylcyanamide (II) proceeds by heterocyclization to afford the 2-benzoylaminopyrimidines (III) which can be debenzoylated without purification to the 2-aminopyrimidines (IV).

chemical structure image

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