Natural Products
Full Access
ChemInform Abstract: Total Synthesis of Both Enantiomers of 15-Oxopuupehenol Methylenedioxy Derivatives.
First published: 24 June 2010
Abstract
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract
The total synthesis of enantiopure methylenedioxy derivatives such as (VI) and (VII) of the cytotoxic, antiviral and antifungal puupehenone and the antitumor, antimalarial and Topoisomerase II inhibition active oxopuupehenol is reported. Key steps are the regioselective dehydration of the alcohol (IV) and the stereoselective cyclization of (V).
