Volume 29, Issue 1
Preparative Organic Chemistry
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ChemInform Abstract: Effective Transformation of Aldoximes to Nitriles by Dehydration with 2-Methylene-1,3-dioxepane in the Presence of a Lewis Acid Catalyst.

S. FUKUZAWA

S. FUKUZAWA

Dep. Appl. Chem., Fac. Sci. Eng., Chuo Univ., Bunkyo, Tokyo 112, Japan

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Y. YAMAISHI

Y. YAMAISHI

Dep. Appl. Chem., Fac. Sci. Eng., Chuo Univ., Bunkyo, Tokyo 112, Japan

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H. FURUYA

H. FURUYA

Dep. Appl. Chem., Fac. Sci. Eng., Chuo Univ., Bunkyo, Tokyo 112, Japan

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K. TERAO

K. TERAO

Dep. Appl. Chem., Fac. Sci. Eng., Chuo Univ., Bunkyo, Tokyo 112, Japan

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F. IWASAKI

F. IWASAKI

Dep. Appl. Chem., Fac. Sci. Eng., Chuo Univ., Bunkyo, Tokyo 112, Japan

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First published: 24 June 2010

Abstract

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ChemInform Abstract

An effective conversion of a variety of aldoximes (I) to the corresponding nitriles is achieved by reaction with 2-methylene-1,3-dioxepane followed by Lewis acid mediated decomposition.

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