Volume 28, Issue 50
Natural Products
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ChemInform Abstract: New Synthesis and Antitumor Activity of cycloSal-Derivatives of 5- Fluoro-2′-deoxyuridinemonophosphate.

M. LOREY

M. LOREY

Inst. Org. Chem., Johann Wolfgang Goethe-Univ., D-60439 Frankfurt/M., Germany

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C. MEIER

C. MEIER

Inst. Org. Chem., Johann Wolfgang Goethe-Univ., D-60439 Frankfurt/M., Germany

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E. DE CLERCQ

E. DE CLERCQ

Inst. Org. Chem., Johann Wolfgang Goethe-Univ., D-60439 Frankfurt/M., Germany

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J. BALZARINI

J. BALZARINI

Inst. Org. Chem., Johann Wolfgang Goethe-Univ., D-60439 Frankfurt/M., Germany

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First published: 02 August 2010

Abstract

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ChemInform Abstract

In search of intracellular active prodrug systems of the title compound, derivatives (III) and (IV) are prepared. Surprisingly they do not reach the expected activity and cannot serve as the desired prodrug forms.

chemical structure image

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