Volume 28, Issue 50
Natural Products
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ChemInform Abstract: Synthesis of (-)-Pseudoconhydrine Through Ring Enlargement of a L- Proline Derivative.

J. COSSY

J. COSSY

Lab. Chim. Org., CNRS, Ec. Super. Phys. Chim. Ind., F-75231 Paris, Fr.

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C. DUMAS

C. DUMAS

Lab. Chim. Org., CNRS, Ec. Super. Phys. Chim. Ind., F-75231 Paris, Fr.

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D. GOMEZ PARDO

D. GOMEZ PARDO

Lab. Chim. Org., CNRS, Ec. Super. Phys. Chim. Ind., F-75231 Paris, Fr.

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First published: 02 August 2010

Abstract

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ChemInform Abstract

Treatment of the L-proline-derived 2,5-disubstituted pyrrolidine (II) results in a tandem aziridine formation-ring enlargement sequence to yield (-)-pseudoconhydrine (IIIb) after debenzylation.

chemical structure image

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