Volume 28, Issue 50
Natural Products
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ChemInform Abstract: An Alternative Efficient Synthesis of the C20-C25 Building Unit for Calyculin A.

M. KABEYA

M. KABEYA

Fac. Pharm. Sci., Nagoya City Univ., Mizuho, Nagoya 467, Japan

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Y. HAMADA

Y. HAMADA

Fac. Pharm. Sci., Nagoya City Univ., Mizuho, Nagoya 467, Japan

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T. SHIOIRI

T. SHIOIRI

Fac. Pharm. Sci., Nagoya City Univ., Mizuho, Nagoya 467, Japan

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First published: 02 August 2010

Abstract

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ChemInform Abstract

The key steps in the synthesis of the C20-C25 building unit (VII) of calyculin A are Wittig reaction of the aldehyde (III) and hydroboration of the resulting olefin (V).

chemical structure image

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