Volume 28, Issue 50
Natural Products
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ChemInform Abstract: The Synthesis of Oxa-Analogues of the Kainoid Family.

H. BAUMGARTNER

H. BAUMGARTNER

Novartis Crop Prot. AG, CH-4002 Basel, Switz.

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A. C. O'SULLIVAN

A. C. O'SULLIVAN

Novartis Crop Prot. AG, CH-4002 Basel, Switz.

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J. SCHNEIDER

J. SCHNEIDER

Novartis Crop Prot. AG, CH-4002 Basel, Switz.

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First published: 02 August 2010

Abstract

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ChemInform Abstract

With a view to obtaining biologically interesting compounds, the title analogues such as (XII) are synthesized. Several approaches for the deprotection of the intermediates (VIII) to the desired products fail. It is interesting that the reaction of (XI) with Zn/HCOOH leads to the corresponding 5-epimers of (XII) exclusively. Compounds (XII) do not show anthelmintic or insecticidal activity.

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