ChemInform Abstract: Synthesis of Fused 1,2,5-Triazepine-1,5-diones and Some N2- and N3- Substituted Derivatives: Potential Conformational Mimetics for cis- Peptidyl Prolinamides.
Abstract
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ChemInform Abstract
A method for the preparation of novel fused triazepine derivatives is presented. Both N-2 and N-3 of the title compounds can be elaborated to give constrained cis-peptidyl proline peptide mimetics of defined stereochemistry.