Heterocyclic Compounds
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ChemInform Abstract: Aminoenylesters. Part 1. A New Synthesis of 1,2,3,4- Tetrahydropyrimidines by Heterocyclic Anellation Reactions of Aminoenylesters with Primary Amines and Acetaldehyde.
First published: 02 August 2010
Abstract
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ChemInform Abstract
A novel heterocyclization reaction is presented. Reaction of the methyl propiolate (I) with primary amines (II) gives the enamines (III) which on coupling with acetaldehyde and primary amines produce tetrahydropyrimidines (V) in moderate to high yields.
