ChemInform Abstract: Synthesis of Analogues of 2-Methoxyestradiol with Enhanced Inhibitory Effects on Tubulin Polymerization and Cancer Cell Growth.
Abstract
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ChemInform Abstract
Among a series of 6-keto, -oximino, -hydrazono, and -amino derivatives, compounds (I), which have negligible estrogen receptor affinities, are of interest for in vivo investigation as anticancer agents, along with 2-ethoxyestradiol.