ChemInform Abstract: Chemical Transformation of 1,8-Cineole. Synthesis of N-Phenylimides from Cineolic Acid.
Abstract
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ChemInform Abstract
Cineolic acid monophenyl ester (I) is regioselectively converted into the corresponding N-arylimides (IV) in two steps. The regioselectivity of some of the reactions and the heterocyclic ring conformations are established based on spectroscopic data. Imides (IV) are unstable in contact with moisture and undergo regioselective hydrolysis.