Volume 28, Issue 31
Heterocyclic Compounds
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ChemInform Abstract: Relationships Between the Chemical Structure of Substances and Their Antimycobacterial Activity to Atypical Strains. Part 9. A New Pharmacophore of Potential Antimycobacterial Activity: The Disulfide Group in the Ring of Alicyclic Compounds.

H.-D. STACHEL

H.-D. STACHEL

Dep. Inorg. Org. Chem., Fac. Pharm., Charles Univ., CZ-500 05 Hradec Kralove, Czech Republic

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Z. ODLEROVA

Z. ODLEROVA

Dep. Inorg. Org. Chem., Fac. Pharm., Charles Univ., CZ-500 05 Hradec Kralove, Czech Republic

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K. WAISSER

K. WAISSER

Dep. Inorg. Org. Chem., Fac. Pharm., Charles Univ., CZ-500 05 Hradec Kralove, Czech Republic

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First published: 03 August 2010

Abstract

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ChemInform Abstract

In order to extend the knowledge of an earlier described pharmacophore for the title activity a series of compounds such as (I) is tested for their antimycobacterial activity and a Free-Wilson structure-activity analysis is discussed.

chemical structure image

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