ChemInform Abstract: Enantioselective Syntheses of No-Carrier-Added (n.c.a.) (S)-4-Chloro-2- (18F)fluorophenylalanine and (S)-(α-Methyl)-4-chloro-2-(18F) fluorophenylalanine.
Abstract
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ChemInform Abstract
The title compounds (IV) are synthesized and labeled with no carrier added 18F by a radiochemical synthesis relying on the highly enantioselective reaction between (18F)fluorobenzyl iodide (I) and the lithium enolate of imidazolidines (II).