Volume 28, Issue 16
Natural Products
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ChemInform Abstract: Enantioselective Syntheses of No-Carrier-Added (n.c.a.) (S)-4-Chloro-2- (18F)fluorophenylalanine and (S)-(α-Methyl)-4-chloro-2-(18F) fluorophenylalanine.

M. J. AL-DARWICH

M. J. AL-DARWICH

Cyclotron Res. Cent., Liege Univ., B-4000 Liege, Belg.

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A. PLENEVAUX

A. PLENEVAUX

Cyclotron Res. Cent., Liege Univ., B-4000 Liege, Belg.

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C. LEMAIRE

C. LEMAIRE

Cyclotron Res. Cent., Liege Univ., B-4000 Liege, Belg.

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G. D. FIORE

G. D. FIORE

Cyclotron Res. Cent., Liege Univ., B-4000 Liege, Belg.

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L. CHRISTIAENS

L. CHRISTIAENS

Cyclotron Res. Cent., Liege Univ., B-4000 Liege, Belg.

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D. COMAR

D. COMAR

Cyclotron Res. Cent., Liege Univ., B-4000 Liege, Belg.

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A. LUXEN

A. LUXEN

Cyclotron Res. Cent., Liege Univ., B-4000 Liege, Belg.

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First published: 04 August 2010

Abstract

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ChemInform Abstract

The title compounds (IV) are synthesized and labeled with no carrier added 18F by a radiochemical synthesis relying on the highly enantioselective reaction between (18F)fluorobenzyl iodide (I) and the lithium enolate of imidazolidines (II).

chemical structure image

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