Heterocyclic Compounds
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ChemInform Abstract: Lewis Acid Mediated Cyclization of β-Phenylethylamides with an Unactivated Benzene Ring: An Efficient Preparation of Dihydroisoquinolines.
First published: 04 August 2010
Abstract
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ChemInform Abstract
A simple protocol for the ZnCl2-mediated dihydroisoquinoline ring formation from β-phenylethylamides, which is suitable for the large-scale preparation of some important drug intermediates, is reported.
