Volume 28, Issue 15
Heterocyclic Compounds
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ChemInform Abstract: New Fused Indole Derivatives from Lactam-Containing m-Cyclophanes.

R. REZAIE

R. REZAIE

Dep. Chem., Univ. Wollongong, Wollongong, N. S. W. 2522, Australia

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J. B. BREMNER

J. B. BREMNER

Dep. Chem., Univ. Wollongong, Wollongong, N. S. W. 2522, Australia

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First published: 04 August 2010

Abstract

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ChemInform Abstract

As part of a program aimed at the functionalizing of the bridging chain of m-cyclophanes, a new approach to seven-membered ring-fused indole derivatives through NBS-bromination of the m-cyclophane-lactam ( I) is discovered. Interestingly, the Boc-protected educt (VII) leads to a single product (VIII) brominated at the benzylic position.

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