ChemInform Abstract: Synthesis and Antibacterial Activity of 2-(Isoxazolidinio-5-yl) carbapenem Derivatives.
Abstract
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ChemInform Abstract
It is ascertained that the antibacterial activity of 1β- methylcarbapenem derivatives, e.g. (VIII), is superior to that of the corresponding 1H-carbapenem derivatives derived from (IIIa). The antibacterial activity of (VIII) is slightly better than that of the corresponding diastereomer derived from (VI).