ChemInform Abstract: Stereochemical Investigation of Aldol Condensations Using (3R)- and ( 3S)-3-Benzylpiperazine-2,5-dione Derivatives.
Abstract
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ChemInform Abstract
The title investigation is carried out in order to study the influence of epimerization at the C-3 position of piperazine-2,5-dione (I) on the asymmetric induction in aldol additions at the C-6 position. The configuration of the new stereocenters are assigned by spectroscopical means and conformational analysis.