ChemInform Abstract: An Iminophosphorane-Mediated Efficient Synthesis of 2,5-Disubstituted- 4,5-dihydroimidazoles.
Abstract
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ChemInform Abstract
The aza-Wittig reaction of β-acetoxyazides (I) with isocyanates ( II) or acyl chlorides (IV) followed by treatment with ammonia provides a one-pot synthesis of title imidazoles (III) and (V), structural fragments of a series of natural compounds.