Volume 27, Issue 11
Heterocyclic Compounds
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ChemInform Abstract: An Iminophosphorane-Mediated Efficient Synthesis of 2,5-Disubstituted- 4,5-dihydroimidazoles.

P. MOLINA

P. MOLINA

Dep. Quim. Org., Fac. Quim., Univ. Murcia, E-30071 Murcia, Spain

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I. DIAZ

I. DIAZ

Dep. Quim. Org., Fac. Quim., Univ. Murcia, E-30071 Murcia, Spain

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A. TARRAGA

A. TARRAGA

Dep. Quim. Org., Fac. Quim., Univ. Murcia, E-30071 Murcia, Spain

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First published: March 12, 1996

Abstract

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ChemInform Abstract

The aza-Wittig reaction of β-acetoxyazides (I) with isocyanates ( II) or acyl chlorides (IV) followed by treatment with ammonia provides a one-pot synthesis of title imidazoles (III) and (V), structural fragments of a series of natural compounds.

chemical structure image

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