ChemInform Abstract: Studies on Cardiac Ingredients of Plants. Part 11. Synthesis of New Bufotoxin Homologues Utilizing Scillarenin (the Genuine Aglycone of Proscillaridin), and Their Biological Activities.
Abstract
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ChemInform Abstract
In order to test their biological activity, the new title compounds such as (I) with different chain lengths are synthesized starting from the known proscillaridin. These new compounds show minimal vascular contractile effects and may be useful as cardiac agents (biological results are given).