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ChemInform Abstract: Prostaglandin Chemistry. Part 43. Studies on the Preparation of Isocarbacyclin Intermediates. Part 2.
First published: May 9, 1995
Abstract
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ChemInform Abstract
2,2,2-Trifluoroethanol is found to be the most effective proton source for the reductive cyclization of the aldehyde (I) with lithium naphthalene leading to the precursors (II) and (III) of the prostacyclin mimic isocarbacyclin.
