ChemInform Abstract: Synthesis of New Thiazinoindole Derivatives and Their Evaluation as Inhibitors of Human Leukocyte Elastase and Other Related Serine Proteases.
Abstract
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ChemInform Abstract
With a view to testing the title biological activity the new heterocyclic compounds such as (IV) and (V) are synthesized starting from the indole derivative (I). The obtained compounds represent a new class of serine protease inhibitors from which more potent and specific inhibitors may be derived.