Natural Products
Full Access
ChemInform Abstract: Activated Ketones as Potent Reversible Inhibitors of Interleukin-1. beta. Converting Enzyme.
First published: February 28, 1995
Abstract
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract
The title ketones, e.g. (VI), are evaluated for their inhibitory activity against Interleukin-1β Converting Enzyme (ICE). The heteroatom in the side chain of (VI) causes an improvement in inhibitory activity compared with that of the corresponding carba analogue.
