ChemInform Abstract: 5-Aryl-β,γ-butenolide, a New Class of Antibacterial Derived from the N-Aryl Oxazolidinone DUP 721.
Abstract
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ChemInform Abstract
The three analogues (IX)-(XI) of DUP 721 are evaluated for their antibacterial activity. Replacement of the oxazolidinone ring of DUP 721 by a β,γ-butenolide results in compound (IX) with similar antibiotic activity.