Isocyclic Compounds
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ChemInform Abstract: A Method for the Cyclic Enone Synthesis Using Lithium Chloride - Hexamethylphosphoramide System.
First published: February 28, 1995
Abstract
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ChemInform Abstract
The α,β-unsaturated ketones (I) undergo a mild lithium chloride mediated reaction under neutral conditions with the β- keto esters (II) to yield the cyclic enones (III) via consecutive Michael addition, decarboxylation, and aldol condensation.
