Volume 26, Issue 1
Heterocyclic Compounds
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ChemInform Abstract: Stereoselective Addition Reactions of Lithiated 2-Chloro-1,3-dithiane- 1,3-dioxide to Aldehydes.

V. K. AGGARWAL

V. K. AGGARWAL

Dep. Chem., Univ. Sheffield, Sheffield S3 7HF, UK

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J. M. WORRALL

J. M. WORRALL

Dep. Chem., Univ. Sheffield, Sheffield S3 7HF, UK

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H. ADAMS

H. ADAMS

Dep. Chem., Univ. Sheffield, Sheffield S3 7HF, UK

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R. ALEXANDER

R. ALEXANDER

Dep. Chem., Univ. Sheffield, Sheffield S3 7HF, UK

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First published: January 3, 1995

Abstract

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ChemInform Abstract

In contrast to dithiane dioxide, its chloro analogue (I) is a suitable substrate for the title reaction. With aromatic aldehydes a good to excellent stereoselectivity is observed at the β-position. These results may open the way to corresponding chiral synthons.

chemical structure image

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