ChemInform Abstract: Stereoselective Addition Reactions of Lithiated 2-Chloro-1,3-dithiane- 1,3-dioxide to Aldehydes.
Abstract
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ChemInform Abstract
In contrast to dithiane dioxide, its chloro analogue (I) is a suitable substrate for the title reaction. With aromatic aldehydes a good to excellent stereoselectivity is observed at the β-position. These results may open the way to corresponding chiral synthons.