ChemInform Abstract: 1,4-Diazabicyclo(2.2.2)octane (DABCO)-catalyzed Hydrolysis and Alcoholysis Reactions of 2-Amino-9-benzyl-6-chloro-9H-purine.
Abstract
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ChemInform Abstract
The title compound (I) reacts by the use of DABCO in a mild and efficient process with hydroxide ion or alcohols such as (III) to 9- substituted guanines (II) and 6-alkoxy-purines (IV), respectively.