Volume 25, Issue 32
Preparative Organic Chemistry
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ChemInform Abstract: An Unprecedented Cleavage of the β-Lactam Ring: Stereoselective Synthesis of Chiral β-Amido Cyanides.

Y. KITA

Y. KITA

Fac. Pharm. Sci., Osaka Univ., Suita, Osaka 565, Japan

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N. SHIBATA

N. SHIBATA

Fac. Pharm. Sci., Osaka Univ., Suita, Osaka 565, Japan

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N. YOSHIDA

N. YOSHIDA

Fac. Pharm. Sci., Osaka Univ., Suita, Osaka 565, Japan

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N. KAWANO

N. KAWANO

Fac. Pharm. Sci., Osaka Univ., Suita, Osaka 565, Japan

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K. MATSUMOTO

K. MATSUMOTO

Fac. Pharm. Sci., Osaka Univ., Suita, Osaka 565, Japan

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First published: August 9, 1994

Abstract

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ChemInform Abstract

A new method is developed for the synthesis of chiral β-amido cyanides of types (III) and (IV) as well as (VII) and (VIII) by means of the regioselective cleavage of β-lactams of types (I) and (V).

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