Volume 25, Issue 13
Natural Products
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ChemInform Abstract: Synthesis and Antiviral Activity of 5′-Deoxypyrazofurin.

X. CHEN

X. CHEN

Dep. Chem., Univ. South Fla., Tampa, FL 33620-5250, USA

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S. W. SCHNELLER

S. W. SCHNELLER

Dep. Chem., Univ. South Fla., Tampa, FL 33620-5250, USA

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S. IKEDA

S. IKEDA

Dep. Chem., Univ. South Fla., Tampa, FL 33620-5250, USA

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R. SNOECK

R. SNOECK

Dep. Chem., Univ. South Fla., Tampa, FL 33620-5250, USA

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G. ANDREI

G. ANDREI

Dep. Chem., Univ. South Fla., Tampa, FL 33620-5250, USA

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J. BALZARINI

J. BALZARINI

Dep. Chem., Univ. South Fla., Tampa, FL 33620-5250, USA

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E. DE CLERCQ

E. DE CLERCQ

Dep. Chem., Univ. South Fla., Tampa, FL 33620-5250, USA

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First published: March 29, 1994

Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

ChemInform Abstract

To find derivatives of pyrazofurin with antiviral properties the 5′- deoxypyrofurazin (VI) is synthesized and tested against a large number of viruses including HIV, HSV and CMV. In some virus strains the compound (VI) is proved to be active at concentrations of 4 to 20 μ g/ml.

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