ChemInform Abstract: Synthesis and Antiviral Activity of 5′-Deoxypyrazofurin.
Abstract
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ChemInform Abstract
To find derivatives of pyrazofurin with antiviral properties the 5′- deoxypyrofurazin (VI) is synthesized and tested against a large number of viruses including HIV, HSV and CMV. In some virus strains the compound (VI) is proved to be active at concentrations of 4 to 20 μ g/ml.