Volume 25, Issue 13
Preparative Organic Chemistry
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ChemInform Abstract: Directed Asymmetric Reduction of a Carbonyl Group via a New Homochiral Boronate Ester.

R. J. MEARS

R. J. MEARS

Dep. Chem., Univ. Manchester Inst. Sci. Technol., Manchester M60 1QD, UK

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A. WHITING

A. WHITING

Dep. Chem., Univ. Manchester Inst. Sci. Technol., Manchester M60 1QD, UK

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First published: March 29, 1994

Abstract

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ChemInform Abstract

Reduction of the homochiral β-boronate ketone (I) by means of borane-THF complex produces enantioselectively the diol (II) after oxidative work-up.

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