Volume 24, Issue 32
Heterocyclic Compounds
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ChemInform Abstract: A Highly Stereoselective Preparation of a Novel Class of Vinyl Epoxides from α-Allenic Alcohols.

R. W. FRIESEN

R. W. FRIESEN

Merck Frosst Centre Therap. Res., Pointe Claire-Dorval, Quebec, Can. H9R 4P8

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M. BLOUIN

M. BLOUIN

Merck Frosst Centre Therap. Res., Pointe Claire-Dorval, Quebec, Can. H9R 4P8

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First published: August 10, 1993

Abstract

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ChemInform Abstract

Reaction of the allenes (I) with elemental iodine gives an E/Z-mixture of the diiodides (II) which are diastereoselectively converted to the trans-configurated oxiranes (III) upon treatment with a base.

chemical structure image

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