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ChemInform Abstract: 1-Deaza-2′-deoxyadenosine: Phosphonate and Phosphoramidite Building Blocks for Solid-Phase Oligonucleotide Synthesis.
First published: April 6, 1993
Abstract
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ChemInform Abstract
The diprotected 1-deaza-2′-deoxyadenosine derivative (I) is converted to the phosphonate (II) or the β-cyanoethyl phosphoramidite (IV). (II) is employed in the solid-phase oligonucleotide synthesis.
