ChemInform Abstract: Enantio- and Diastereoselective Synthesis of (R-(R*,R*))-α-1,3- Benzodioxol-5-yl-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo(4,5-g) isoquinolin-5-ylmethanol from D-Ribonolactone.
Abstract
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ChemInform Abstract
The newly isolated alkaloid epi-α-decumbensine, i.e. the title compound (X), is prepared with high enantioselectivity. A recent synthesis offered stereoselectivity at a key step in the range of 30% e.e.