Volume 23, Issue 22
Heterocyclic Compounds
Full Access

ChemInform Abstract: Formation of 2,5-Dihydro-3H-pyrazolo(4,3-c)quinolin-3-ones from Ethyl 3-Anilino-2-(2-tert-butyl-2H-tetrazol-5-yl)acrylates.

S. ISODA

S. ISODA

Tokyo RPD Center, Daiichi Pharm. Co., Ltd., Tokyo 134, Japan

Search for more papers by this author
H. KANNO

H. KANNO

Tokyo RPD Center, Daiichi Pharm. Co., Ltd., Tokyo 134, Japan

Search for more papers by this author
First published: June 2, 1992

Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

ChemInform Abstract

Coupling of the arylamines (I) with the tetrazole-substituted acrylate (II) forms the β-arylaminoacrylates (III) which are cyclized in refluxing diphenyl ether to form the pyrazolo-fused quinolinones (IV) mentioned in the title. A mechanism involving the loss of nitrogen is proposed. The tetrazole derivative (V) yields the tetrazolylquinolone ( VI) under these cyclization conditions.

chemical structure image

    The full text of this article hosted at iucr.org is unavailable due to technical difficulties.