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ChemInform Abstract: Synthesis of Conformationally Restricted Chiral γ-Aminobutyric Acid (GABA) Analogues.
First published: April 16, 1991
Abstract
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ChemInform Abstract
The title compounds (VIII) and (IX) are prepared from the homoserine lactone (I). The analogous preparation of a bicyclic analogue from the hydroxyproline lactone (X) is unsuccessful, because in the last reaction step the ester (XI) cannot be cyclized (yield of (VII) given in g).
