Organoelement Compounds
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ChemInform Abstract: Application of AMPP-Pd Catalysts in an Unusual Asymmetric Allylic Coupling Reaction of 1-(Trimethylsilyl)vinylmagnesium Bromide.
First published: September 11, 1990
Abstract
The palladium complex catalyzed reaction of trimethylsilylvinylmagnesium bromide (I) with the cyclohexenyl acetate (II) yields the trimethylsilylvinylcyclohexene (III) which can be used as a versatile synthon.
ChemInform Abstract
The palladium complex catalyzed reaction of trimethylsilylvinylmagnesium bromide (I) with the cyclohexenyl acetate (II) yields the trimethylsilylvinylcyclohexene (III) which can be used as a versatile synthon. When a catalyst with a chiral ligand is applied, a remarkable enantiomeric excess of one optical isomer is produced as shown for the reaction conditions C) or D). Further different conditions are given in the original paper.
