Heterocyclic Compounds
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ChemInform Abstract: Synthesis of 4-Oxo-4H-pyrido(3′,2′:4,5)furo(3,2-d)-1,3-oxazines.
First published: September 11, 1990
Abstract
The 2-pyridone derivatives (I) are O-alkylated with ethyl chloroacetate (II) to yield the pyridyl ethers (III) which are cyclized, forming the furo(2,3-b)pyridine derivatives (IV).
ChemInform Abstract
The 2-pyridone derivatives (I) are O-alkylated with ethyl chloroacetate (II) to yield the pyridyl ethers (III) which are cyclized, forming the furo(2,3-b)pyridine derivatives (IV). Acylation of the 3-amino group, hydrolysis of the ester, and cyclization of the acids (VII) obtained give the title compounds (VIII).
