Isocyclic Compounds
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ChemInform Abstract: Synthesis of Tricyclospirodienones via Spiroannulation. Methodology for Synthesis of Aromatase Inhibitors.
First published: September 11, 1990
ChemInform Abstract
The methoxytetralincarboxylic acid chlorides (IV) and (X), prepared from 6-methoxy-1-tetralone (I) or from the cyanomethoxybenzocyclobutene (VII) as outlined in the reaction scheme, undergo cyclization reaction with the terminal alkynes (V) in the presence of aluminum trichloride, forming the fused cyclopentenones (VI) or (XI).
