Isocyclic Compounds
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ChemInform Abstract: Synthesis of 2,6-Disubstituted Dihydronaphthalenes and Naphthalenes by Electrocyclic Reaction of o-Quinodimethane. A Synthesis of (.+-.)-Naproxen.
First published: July 3, 1990
Abstract
A way to form dihydrobenzocyclobutenes such as (V) in good yield is described.
ChemInform Abstract
A way to form dihydrobenzocyclobutenes such as (V) in good yield is described. These compounds undergo thermolysis giving o-quinodimethanes as intermediates, which generate the products (VI) or (VII) by electrocyclic reaction. Some examples of this reaction are reported. The compound (VIIb) is an efficient precursor for (±)-naproxen (IX).
