Volume 21, Issue 22
Natural Products
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ChemInform Abstract: Cephalosporins to Carbapenems: 1-Oxygenated Carbapenems and Carbapenams.

R. L. ROSATI

R. L. ROSATI

Cent. Res. Div., Pfizer Inc., Groton, CT 06340, USA

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L. V. KAPILI

L. V. KAPILI

Cent. Res. Div., Pfizer Inc., Groton, CT 06340, USA

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P. MORRISSEY

P. MORRISSEY

Cent. Res. Div., Pfizer Inc., Groton, CT 06340, USA

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J. A. RETSEMA

J. A. RETSEMA

Cent. Res. Div., Pfizer Inc., Groton, CT 06340, USA

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First published: May 29, 1990

Abstract

Photo-induced Wolff rearrangement of diazocephem oxides such as (I) yields directly 1-oxocarbapen-2-ems such as (II).

ChemInform Abstract

Photo-induced Wolff rearrangement of diazocephem oxides such as (I) yields directly 1-oxocarbapen-2-ems such as (II). The latter is transformed into the hydrogenated derivatives (III) and (IV).

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