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ChemInform Abstract: Oxidation of Enamines Derived from Sugars.
First published: February 20, 1990
Abstract
The oxidation of 7 sugar enamines such as (I) with KMnO4/NaIO4 is described.
ChemInform Abstract
The oxidation of 7 sugar enamines such as (I) with KMnO4/NaIO4 is described. While 2'-monosubstituted enamines (R2 = H) such as (Ia) yield the N-formyl amino sugar (II), the 2',2'-disubstituted enamines (R2 ≠ H) such as (Ib) afford the α-hydroxy amide (III) as main product. E/Z-Isomerism is observed for the NH-CHO moiety of the formyl amino sugars (II).
