Heterocyclic Compounds
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ChemInform Abstract: 6-(Substituted Phenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-ones of Medicinal Interest. The Synthesis of SK&F 94836 und SK&F 95654.
First published: August 15, 1989
Abstract
The dihydropyridazinones (XII) and (XVIII) mentioned in the title are prepared as shown in the reaction scheme.
ChemInform Abstract
The dihydropyridazinones (XII) and (XVIII) mentioned in the title are prepared as shown in the reaction scheme. The key step is the cyclocondensation of the γ-keto acid derivatives (VII) and (XVII) with hydrazine hydrate (VIII).
