Isocyclic Compounds
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ChemInform Abstract: The Chemistry of Benzotriazole. Part 9. A Conceptually New Approach to the Synthesis of Secondary Amides and Thioamides.
First published: May 30, 1989
Abstract
The benzotriazolyl (thio)amides (I), prepared by condensation reaction of benzotriazole (IV), aldehydes, and (thio)amides, undergo substitution reaction with the Grignard reagents (II), producing the secondary (thio)amides (III).
ChemInform Abstract
The benzotriazolyl (thio)amides (I), prepared by condensation reaction of benzotriazole (IV), aldehydes, and (thio)amides, undergo substitution reaction with the Grignard reagents (II), producing the secondary (thio)amides (III). Alkaline work-up removes (IV) from the reaction mixture.
