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ChemInform Abstract: A Reexamination of the Synthesis of Paracetamol Glucuronide, the Major Urinary Metabolite of Paracetamol in Man.
First published: May 2, 1989
Abstract
The title compound (V) can be efficiently prepared starting either from the (tetra-O-acetyl glucopyranoside)uronate (I) or (tri-O-acetyl glucopyranosyl bromide)-uronate (III) via the condensation product (IV).
ChemInform Abstract
The title compound (V) can be efficiently prepared starting either from the (tetra-O-acetyl glucopyranoside)uronate (I) or (tri-O-acetyl glucopyranosyl bromide)-uronate (III) via the condensation product (IV). Depending on the work-up conditions, either (V) or its more stable Na salt can be obtained after alkaline hydrolysis.
