Isocyclic Compounds
Full Access
ChemInform Abstract: The Directed ortho-Metalation Connection to Aryl-Aryl Cross Coupling. A General Regiospecific Synthesis of Phenanthrols.
First published: May 2, 1989
Abstract
The arylboronic acids (I) are coupled with the o-bromotoluenes (II) in the presence of a Pd catalyst and subsequently with LDA to yield the phenanthrols (IV).
ChemInform Abstract
The arylboronic acids (I) are coupled with the o-bromotoluenes (II) in the presence of a Pd catalyst and subsequently with LDA to yield the phenanthrols (IV). Some of their derivatives, e.g. (V) and (VII), are subjected to further modifications. The boronic acid (XI) reacts with p-bromonitrobenzene (XII) under palladium catalysis, producing the biaryl (XIII).
