Volume 20, Issue 18
Preparative Organic Chemistry
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ChemInform Abstract: LiBH4(NaBH4)/Me3SiCl, an Unusually Potent and Versatile Reduction Agent.

A. GIANNIS

A. GIANNIS

Inst. Org. Chem. Biochem., Univ., D-5300 Bonn 1

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K. SANDHOFF

K. SANDHOFF

Inst. Org. Chem. Biochem., Univ., D-5300 Bonn 1

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First published: May 2, 1989

Abstract

The title reagents (cf.

ChemInform Abstract

The title reagents (cf. the conditions A) or B)) are efficient for the reduction of amino acids such as (Ia), carboxylic acids such as (Ib), amides such as (Ic), (Id), or nitriles such as (III). The nitrostyrene derivative (V) or the sulfoxide (VII) are reduced to the compounds (VI) or (VIII).

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